| Departure: | Poughkeepsie, NY | 
| Arrival: | Buffalo, NY | 
| Fastest route: | 6h 29min | 
| Distance: | 492km | 
| Cheapest route: | $63 | 
| Transfers: | 0 | 
| Train companies: | Amtrak | 
One Passenger / One Trip
8:45am
Poughkeepsie, NY
Poughkeepsie
3:14pm
Buffalo, NY
Buffalo - Exchange St.
6h 29min
Amtrak
Maple Leaf
$63
11:43am
Poughkeepsie, NY
Poughkeepsie
6:24pm
Buffalo, NY
Buffalo - Exchange St.
6h 41min
Amtrak
Empire Service
$63
2:45pm
Poughkeepsie, NY
Poughkeepsie
9:23pm
Buffalo, NY
Buffalo - Exchange St.
6h 38min
Amtrak
Empire Service
$63
          The Poughkeepsie - Buffalo route has approximately 3 frequencies and its minimum duration is around 6h 29min. It is important you book your ticket in advance to avoid running out, since $63 tickets tend to run out quickly. 
 The distance between Poughkeepsie and Buffalo is around 492 kilometers and bus companies that can help you in your journey are: Amtrak.
          
        
The train journey may vary depending on the stops. The minimum duration is usually around 6h 29min to cover 492 kilometers.
According to our data, the cheapest ticket costs $63 and leaves Poughkeepsie. You will not have to do any transfers, the trip will go direct to Buffalo - Exchange St..
The last train leaves at 2:45pm from Poughkeepsie and arrives at 9:23pm at Buffalo - Exchange St.. It will take 6h 38min, its price is $63 and the number of changes will be 0.
Yes, there are direct train routes, their duration is usually around 6h 29min and the price is $63.